![]() ![]() No sporozoite infections were detected in intervention areas after IRS and biting rates by An. arabiensis accounted for 86% of Anopheles collected by PSC and 66% by CDC light trap in the sprayed sites while the proportion in non-intervention sites remained unchanged. funestus accounted for over 80% of Anopheles mosquitoes collected by light trap and PSC in all sites. arabiensis collected by PSC were 69% in the intervention compared to the non-intervention areas (RR = 0.31, 0.14–0.68, p = 0.006), but there was no significant difference with light traps (RR = 0.45, 0.21–0.96, p = 0.05). ![]() The corresponding reductions in the numbers of An. funestus numbers in the intervention areas compared to non-intervention areas by 88% with light traps (risk ratio 0.12, 95% CI 0.07–0.21, p < 0.001) and 93% with PSC collections (RR = 0.07, 0.03–0.17, p < 0.001). IRS was associated with reductions in An. Malaria case burden data were extracted from laboratory records of four health facilities within the sprayed area and two adjacent unsprayed areas. ![]() Kisumu strain to sprayed surfaces in cone assays and measuring mortality at 24 hours. The residual effect of the insecticide was assessed monthly by exposing susceptible An. Entomological monitoring was conducted by indoor CDC light trap, pyrethrum spray catches (PSC) and human landing collection (HLC) before and after IRS. We evaluated the impact of a single round of IRS with the organophosphate, pirimiphos-methyl (Actellic 300CS), on entomological and parasitological parameters of malaria in Migori County, western Kenya in 2017, in an area where primary vectors are resistant to pyrethroids but susceptible to the IRS compound. Indoor residual spraying (IRS) of insecticides is a major vector control strategy for malaria prevention.
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